| Career - At Bats | |||
| Rk | Player Name | Totals | |
| 1 | Adam Jones | 5474 | |
| 2 | Victor Martinez | 5246 | |
| 3 | Nolan Arenado | 4933 | |
| 4 | Frank Thomas | 4555 | |
| 5 | Hideki Matsui | 3838 | |
| 6 | Alexei Ramirez | 3145 | |
| 7 | Prince Fielder | 2880 | |
| 8 | John Olerud | 2723 | |
| 9 | Paul O'Neill | 2613 | |
| 10 | Marquis Grissom | 2590 | |
| 11 | Ichiro Suzuki | 2562 | |
| 12 | Vinny Castilla | 2471 | |
| 13 | Edgar Martinez | 2408 | |
| 14 | Corey Hart | 2287 | |
| 15 | Rich Aurilia | 2272 | |
| 16 | Eric Davis | 2251 | |
| 17 | Cedric Mullins | 2206 | |
| 18 | Cameron Maybin | 2200 | |
| 19 | Rusty Greer | 2122 | |
| 20 | Juan Pierre | 2061 | |
| 21 | Charlie Blackmon | 2057 | |
| 22 | Salvador Perez | 2016 | |
| 23 | Joey Cora | 1923 | |
| 24 | Shawn Green | 1910 | |
| 25 | Ryan Doumit | 1870 | |
| Single Season - At Bats | |||||
| Rk | Player Name | Totals | Year | ||
| 1 | Marquis Grissom | 731 | 1994 | ||
| 2 | Charlie Hayes | 704 | 1994 | ||
| 3 | Brandon Phillips | 695 | 2016 | ||
| 4 | Scott Fletcher | 691 | 1994 | ||
| 5 | Ichiro Suzuki | 672 | 2015 | ||
| 6 | Juan Pierre | 668 | 2010 | ||
| 7 | Tony Graffanino | 667 | 2006 | ||
| 8 | Ichiro Suzuki | 667 | 2017 | ||
| 9 | Adam Jones | 666 | 2014 | ||
| 10 | Bret Boone | 665 | 2002 | ||
| 11 | Frank Thomas | 661 | 1991 | ||
| 12 | Dante Bichette | 659 | 2001 | ||
| 13 | Jorge Polanco | 658 | 2020 | ||
| 14 | Corey Hart | 654 | 2012 | ||
| 15 | Jemile Weeks | 654 | 2012 | ||
| 16 | Alexei Ramirez | 654 | 2014 | ||
| 17 | Nolan Arenado | 653 | 2018 | ||
| 18 | Chris Stynes | 652 | 2001 | ||
| 19 | Cameron Maybin | 652 | 2020 | ||
| 20 | Rusty Greer | 651 | 1998 | ||
| 21 | Joey Wendle | 650 | 2019 | ||
| 22 | Gio Urshela | 650 | 2023 | ||
| 23 | Adam Jones | 647 | 2013 | ||
| 24 | Adam Jones | 645 | 2011 | ||
| 25 | Nolan Arenado | 643 | 2020 | ||