| Career - Homeruns | |||
| Rk | Player Name | Totals | |
| 1 | Albert Belle | 292 | |
| 2 | Magglio Ordonez | 184 | |
| 3 | Larry Walker | 177 | |
| 4 | Cal Ripken | 173 | |
| 5 | Phil Nevin | 169 | |
| 6 | David Wright | 158 | |
| 7 | Luis Gonzalez | 155 | |
| 8 | Will Clark | 146 | |
| 9 | Brandon Crawford | 111 | |
| 10 | Matt Kemp | 110 | |
| 11 | Chris Taylor | 100 | |
| 12 | Moises Alou | 88 | |
| 13 | Rich Aurilia | 85 | |
| 14 | Carlos Beltran | 73 | |
| 15 | Aaron Hill | 63 | |
| 16 | Josh Willingham | 62 | |
| 17 | Chuck Knoblauch | 61 | |
| 18 | Brad Miller | 60 | |
| 19 | Scott Rolen | 59 | |
| 20 | Mike Lowell | 59 | |
| 21 | Kevin Pillar | 59 | |
| 22 | Didi Gregorius | 58 | |
| 23 | Luke Scott | 53 | |
| 24 | Wilin Rosario | 53 | |
| 25 | Evan Longoria | 52 | |
| Single Season - Homeruns | |||||
| Rk | Player Name | Totals | Year | ||
| 1 | Luis Gonzalez | 49 | 2002 | ||
| 2 | Albert Belle | 47 | 1999 | ||
| 3 | Albert Belle | 46 | 1994 | ||
| 4 | Max Muncy | 45 | 2019 | ||
| 5 | Yainer Diaz | 44 | 2024 | ||
| 6 | David Wright | 42 | 2011 | ||
| 7 | Albert Belle | 41 | 1995 | ||
| 8 | Phil Nevin | 40 | 2005 | ||
| 9 | Matt Adams | 40 | 2014 | ||
| 10 | Moises Alou | 39 | 2005 | ||
| 11 | Rich Aurilia | 39 | 2002 | ||
| 12 | Phil Nevin | 39 | 2004 | ||
| 13 | Larry Walker | 39 | 1996 | ||
| 14 | Matt Kemp | 39 | 2012 | ||
| 15 | Danny Santana | 39 | 2020 | ||
| 16 | Adrian Beltre | 38 | 2007 | ||
| 17 | Barry Bonds | 38 | 2008 | ||
| 18 | Albert Belle | 36 | 1993 | ||
| 19 | Albert Belle | 36 | 1997 | ||
| 20 | Phil Nevin | 36 | 2001 | ||
| 21 | Cal Ripken | 36 | 1994 | ||
| 22 | Larry Walker | 36 | 1998 | ||
| 23 | Brad Miller | 36 | 2020 | ||
| 24 | Albert Belle | 34 | 1992 | ||
| 25 | Jim Thome | 34 | 2011 | ||